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Metabolic .beta.-hydroxylation and N-oxidation of n'-nitrosonornicotine

โœ Scribed by Hecht, Stephen S.; Chen, Chi-Hong B.; Hoffmann, Dietrich


Book ID
126438230
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
582 KB
Volume
23
Category
Article
ISSN
0022-2623

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Metabolism of Nโ€ฒ-nitrosonornicotine by a
โœ P.P. Chakradeo; J. Nair; S.V. Bhide ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 261 KB

The metabolism of \(\beta\) H)labelled \(N\)-Nitrosonornicotine a major constituent of the class of Tobacco Specific Nitrosamines was studied in adult and fetal human oesophageal cultures. The metabolites were separated by HPLC and were identified when compared to the standards as OH-acid from 5 'hy