Metabolic Basis for the Cholesterol-Lowering Action of Dietary Polyunsaturated Fatty Acids
✍ Scribed by Beynen, A. C. ;Katan, M. B.
- Publisher
- John Wiley and Sons
- Year
- 1986
- Weight
- 382 KB
- Volume
- 88
- Category
- Article
- ISSN
- 0931-5985
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✦ Synopsis
or anxiety than aroutine venipuncture ".The stability ofthe fatty acid composition ofbiopsies has been tested withexcellent results and samples can be stored for at least 18 months without deterioration 13. This indicates that samples can be collected in the field without special precautions as tostorage conditions.
The fatty acid profile of adipose tissue has already been used in various types of research as an indicator of the qualitative fat intake. Dayton et al. l7 used the linoleic acid content of adipose tissue as a criterion of adherence to an experimental diet. We have recently used adipose tissue linoleic acid in order to compare linoleic acid intake in the USA and UK I*.
Furthermore, there is evidence that a low percentage of linoleic acid in subcutaneous adipose tissue correlateswithahigh risk for coronary heart disease 19*20 and a low risk for malignant melanomaZ1.Thus,it appears that thefattyacidcomposition of subcutaneous adipose tissue could be an important tool in various types of nutrition research.