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Metabolic and Renal Changes Following the Ingestion of African Mistletoe Extract in Rats

✍ Scribed by D. K. Obatomi; A. A. A. Oye; Z. N. Jangber; V. J. Temple

Publisher: John Wiley and Sons
Year: 1997
Tongue: English
Weight: 79 KB
Volume: 11
Category: Article
ISSN: 0951-418X
DOI: 10.1002/(sici)1099-1573(199703)11:2<171::aid-ptr60>3.0.co;2-t

No coin nor oath required. For personal study only.

✦ Synopsis

The effect of an aqueous extract of African mistletoe (Loranthus begwensis) from two host plants (Citrus limon [Cl-mistletoe] or Vernonia amygdalina [Va-mistletoe]) was studied in male Wistar rats treated orally with either 1.32, 13.2 or 26.4 g/kg per day for 7 days. A significant dose-dependent reduction (p < 0.01) in the serum glucose and cholesterol was obtained with both extracts, accompanied by a reduction of urine flow rate and serum creatinine. Increases in urinary enzymes and protein excretion were dose-related and dependent on the source of extracts. Mistletoe extract irrespective of source appears to lower the blood sugar level offering the potential for clinical use of the ingredients of its extracts.

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