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Metabolic and analytical interactions of grapefruit juice and 1,2-benzopyrone (coumarin) in man

✍ Scribed by M. Runkel; M. Tegtmeier; W. Legrum

Publisher
Springer
Year
1996
Tongue
English
Weight
300 KB
Volume
50
Category
Article
ISSN
0031-6970

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To investigate the potential interaction between selected ingredients of grapefruit juice and, the transport of talinolol, a P-gp substrate, across Caco-2 cells monolayers was determined in the absence and presence of distinct concentrations of grapefruit juice, bergamottin, 6 0 ,7 0 -dihydroxyberga