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Metabolic analysis of 13C-labeled pyruvate for noninvasive assessment of mitochondrial function

✍ Scribed by I-Chien Wu; Ikuroh Ohsawa; Noriyuki Fuku; Masashi Tanaka

Book ID
111399884
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
373 KB
Volume
1201
Category
Article
ISSN
0890-6564

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Using 13 C-labeled glucose fed to a penicillinoverproducing strain of Penicillium chrysogenum, the intracellular fluxes were quantified, and the presence of two new pathways, not previously described in this organism, is suggested. Thus, glycine was synthesized not only by serine hydroxymethyltransf