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Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: A review

✍ Scribed by Weiling Xue; David Warshawsky

Book ID
113923511
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
799 KB
Volume
206
Category
Article
ISSN
0041-008X

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## Abstract The metabolism of three carcinogenic polycyclic aromatic hydrocarbons was measured in mid‐(population doubling levels of 20–39) and late‐(population doubling levels > 55) passage cultures of WI‐38 human diploid fibroblasts. Cultures of mid‐and late‐passage cells metabolized these hydroc