𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Metabolic activation of drugs in mutagenicity tests in vitro

✍ Scribed by M. B. Roberfroid

Publisher
Springer-Verlag
Year
1980
Tongue
English
Weight
733 KB
Volume
46
Category
Article
ISSN
0340-5761

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Mutagenicity of malachite green and leuc
Mutagenicity of malachite green and leucomalachite green in in vitro tests
✍ V. Fessard; T. Godard; S. Huet; A. Mourot; J. M. Poul πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 193 KB

The genotoxic potential of the fungicide malachite green (MG) and its reduced derivative leucomalachite green (LMG) was assessed in bacteria and mammalian cells using the standard Salmonella typhimurium/Ames and CHO/HGPRT tests. In vitro potential DNA damaging effects of MG and LMG were tested using

Mutagenicity of tetrachloroethene in the
Mutagenicity of tetrachloroethene in the ames testβ€”metabolic activation by conjugation with glutathione
✍ Vamvakas, Spyridon ;Herkenhoff, Martin ;Dekant, Wolfgang ;Henschler, Dietrich πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 649 KB

The mutagenicity of tetrachloroethene (tetra) and its S conjugate, S-(1,2,2-trichlorovinyl)glutathione (TCVG) was investigated using a modified Ames preincubation assay. TCVG was a potent mutagen in presence of rat kidney particulate fractions containing high concentrations of y-glutamyl transpeptid