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Metabolic activation of [14C] polychlorinated biphenyl mixtures by rat liver microsomes

โœ Scribed by Tsutomu Shimada


Book ID
112606686
Publisher
Springer
Year
1976
Tongue
English
Weight
481 KB
Volume
16
Category
Article
ISSN
0007-4861

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Metabolism of polychlorinated dibenzo-p-
โœ Keke Hu; Nigel J. Bunce ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 121 KB ๐Ÿ‘ 1 views

The in vitro metabolism of several chlorinated dibenzo-p-dioxin congeners (PCDDs) was studied using rat liver microsomes as a source of CYP 1 enzymes. The reactions were kinetically first order in both enzyme and substrate and showed a general trend toward decreasing reactivity with increasing chlor