✦ LIBER ✦

Meta-analysis of time-to-event data: a comparison of two-stage methods

✍ Scribed by Mark C. Simmonds; Jayne Tierney; Jack Bowden; Julian PT Higgins

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 214 KB
Volume: 2
Category: Article
ISSN: 1759-2879
DOI: 10.1002/jrsm.44

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Individual patient data meta-analysis of

Individual patient data meta-analysis of time-to-event outcomes: one-stage versus two-stage approaches for estimating the hazard ratio under a random effects model

✍ Jack Bowden; Jayne F Tierney; Mark Simmonds; Andrew J Copas; Julian PT Higgins 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 657 KB

Assessing treatment–time interaction in

Assessing treatment–time interaction in clinical trials with time to event data: a meta-analysis of hypertension trials

✍ F. Boutitie; F. Gueyffier; S. J. Pocock; J. P. Boissel 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 178 KB 👁 3 views

Exploration of the variation of treatment effect over time in randomized clinical trials with low event rates is limited by lack of power. A meta-analysis on individual patient data from such trials can partly solve the problem, but brings other computational difficulties. Using an example in hypert

Explaining heterogeneity in meta-analysi

Explaining heterogeneity in meta-analysis: a comparison of methods

✍ Simon G. Thompson; Stephen J. Sharp 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 160 KB 👁 2 views

Exploring the possible reasons for heterogeneity between studies is an important aspect of conducting a meta-analysis. This paper compares a number of methods which can be used to investigate whether a particular covariate, with a value de"ned for each study in the meta-analysis, explains any hetero

Comparison of imputation methods for int

Comparison of imputation methods for interval censored time-to-event data in joint modelling of tree growth and mortality

✍ Terry C. K. Lee; Leilei Zeng; Darby J. S. Thompson; C. B. Dean 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 French ⚖ 223 KB 👁 1 views

Comparison of One-Step and Two-Step Meta

Comparison of One-Step and Two-Step Meta-Analysis Models Using Individual Patient Data

✍ Thomas Mathew; Kenneth Nordström 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 213 KB

A comparison of population and standard

A comparison of population and standard two-stage pharmacokinetic analyses of vigabatrin data

✍ Dale K. Yu; Sam J. Hutcheson; Greg Wei; Vijay O. Bhargava; Scott J. Weir 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 576 KB

Vigabatrin (VGB), an irreversible inhibitor of GABA, is being developed as an add-on therapy for uncontrolled complex partial seizure. A single-dose study was conducted in three groups of subjects with normal, mild-to-moderate, and moderate-to-severe renal impairment to examine the effect of renal f