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Meta-analysis of the association of β2-adrenergic receptor polymorphisms with asthma phenotypes

✍ Scribed by CONTOPOULOSIOANNIDIS, D; MANOLI, E; IOANNIDIS, J

Book ID: 119275024
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 420 KB
Volume: 115
Category: Article
ISSN: 1097-6825
DOI: 10.1016/j.jaci.2004.12.1119

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## Abstract Both β~1~‐ and β2‐adrenergic receptors (β~1~‐ and β~2~‐AR) have important roles in heart function mainly in response to catecholamines. Some specific polymorphisms in the β~1~‐ and β~2~‐AR genes, named ADRB1 and ADRB2, respectively, have been implicated in several cardiovascular and non