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Meta-analysis of haplotype-association studies: comparison of methods and empirical evaluation of the literature

โœ Scribed by Pantelis G Bagos

Book ID
119894599
Publisher
BioMed Central
Year
2011
Tongue
English
Weight
472 KB
Volume
12
Category
Article
ISSN
1471-2156

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Meta-analysis of genome-wide association studies involves testing single nucleotide polymorphisms (SNPs) using summary statistics that are weighted sums of site-specific score or Wald statistics. This approach avoids having to pool individual-level data. We describe the weights that maximize the pow