Meta-analysis of breast cancer outcome and toxicity in adjuvant trials of aromatase inhibitors in postmenopausal women
β Scribed by Aydiner, Adnan
- Book ID
- 120461932
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 304 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0960-9776
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## Abstract ## BACKGROUND. Despite the advantages from using aromatase inhibitors (AIs) compared with tamoxifen for early breast cancer, an unexpectedly greater number of grade 3 and 4 cardiovascular events (CVAE) (as defined by National Cancer Institute of CanadaβCommon Toxicity Criteria [version
Five years of adjuvant therapy with tamoxifen was considered the gold-standard treatment for postmenopausal women with estrogen receptor-positive breast cancer for many years. Data from a core group of clinical trials investigating the safety and efficacy of aromatase inhibitors (AIs) have challenge