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Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population

✍ Scribed by Okada, Yukinori; Terao, Chikashi; Ikari, Katsunori; Kochi, Yuta; Ohmura, Koichiro; Suzuki, Akari; Kawaguchi, Takahisa; Stahl, Eli A; Kurreeman, Fina A S; Nishida, Nao; Ohmiya, Hiroko; Myouzen, Keiko; Takahashi, Meiko; Sawada, Tetsuji; Nishioka, Yuichi; Yukioka, Masao; Matsubara, Tsukasa; Wakitani, Shigeyuki; Teshima, Ryota; Tohma, Shigeto; Takasugi, Kiyoshi; Shimada, Kota; Murasawa, Akira; Honjo, Shigeru; Matsuo, Keitaro; Tanaka, Hideo; Tajima, Kazuo; Suzuki, Taku; Iwamoto, Takuji; Kawamura, Yoshiya; Tanii, Hisashi; Okazaki, Yuji; Sasaki, Tsukasa; Gregersen, Peter K; Padyukov, Leonid; Worthington, Jane; Siminovitch, Katherine A; Lathrop, Mark; Taniguchi, Atsuo; Takahashi, Atsushi; Tokunaga, Katsushi; Kubo, Michiaki; Nakamura, Yusuke; Kamatani, Naoyuki; Mimori, Tsuneyo; Plenge, Robert M; Yamanaka, Hisashi; Momohara, Shigeki; Yamada, Ryo; Matsuda, Fumihiko; Yamamoto, Kazuhiko

Book ID: 127354862
Publisher: Nature Publishing Group
Year: 2012
Tongue: English
Weight: 722 KB
Volume: 44
Category: Article
ISSN: 1061-4036
DOI: 10.1038/ng.2231

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## Abstract ## Objective Recent studies of 2 complex diseases, rheumatoid arthritis (RA) and Crohn's disease (CD), showed associations with genes mapping to the cytokine gene cluster on 5q31. In particular, a functional single‐nucleotide polymorphism (SNP) mapping to intron 1 of the organic cation