𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Mesoscale conformational changes in the DNA-repair complex Rad50/Mre11/Nbs1 upon binding DNA

✍ Scribed by Moreno-Herrero, Fernando; de Jager, Martijn; Dekker, Nynke H.; Kanaar, Roland; Wyman, Claire; Dekker, Cees


Book ID
109894628
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
461 KB
Volume
437
Category
Article
ISSN
0028-0836

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Intracellular redistribution and modific
✍ Joshua D. Seno; Joseph R. Dynlacht πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 356 KB

## Abstract Mre11, Rad50, and Nbs1form a tight complex which is homogeneously distributed throughout the nuclei of mammalian cells. However, after irradiation, the Mre11/Rad50/Nbs1 (M/R/N) complex rapidly migrates to sites of double strand breaks (DSBs), forming foci which remain until DSB repair i