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Mesoionic purinone analogs. III. The synthesis and properties of mesoionic thiazolo[3,2-a ] pyrimidine-5,7-diones

✍ Scribed by R. A. Coburn; R. A. Glennon


Book ID
112122978
Publisher
Journal of Heterocyclic Chemistry
Year
1973
Tongue
English
Weight
540 KB
Volume
10
Category
Article
ISSN
0022-152X

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## Abstract The synthesis of the first examples of Class II mesoionic thiazolopyrimidine acyclonucleosides (MTA) incorporating the 2,3‐dihydroxypropyl moiety as the sugar simulator is described. First, 2‐bromothiazole was reacted with excess 1‐amino‐2,3‐propanediol acetonide __via__ an aromatic nuc