Mesenchymal stromal cells: filling the void of immunosuppressive therapy in aplastic anemia?
β Scribed by Scheinberg, Phillip
- Book ID
- 122428707
- Publisher
- Informa plc
- Year
- 2013
- Tongue
- English
- Weight
- 72 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1465-3249
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π SIMILAR VOLUMES
Previously, we reported that patients with aplastic anemia (AA) have profoundly decreased numbers of hematopoietic progenitor and stem cells as measured in the longterm culture initiating cell (LTC-IC) assay (Blood 1996;88:1983-1991). We now present results of a long-term prospective study of LTC-IC
By using Dexter-type long-term marrow cultures (D-LTMC), it has been shown previously that hematopoietic progenitor cells (HPC) from patients with aplastic anemia (AA) have a deficient proliferation in vitro. The studies reported to date, however, have focused exclusively on granulomonocytic progeni