Mesenchymal stromal cell therapy for steroid-refractory acute and chronic graft versus host disease: a phase 1 study
โ Scribed by Richard Herrmann; Marian Sturm; Kathryn Shaw; Duncan Purtill; Julian Cooney; Matthew Wright; Michael Phillips; Paul Cannell
- Book ID
- 107619396
- Publisher
- Carden Jennings Publishing
- Year
- 2011
- Tongue
- English
- Weight
- 227 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0925-5710
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Acute graft-versus-host disease (GVHD) following orthotopic liver transplantation is a rare but severe disease with a 75% death rate in adults. Various therapeutic strategies have been proposed for steroid-refractory GVHD, but there is still no consensus. Tumor necrosis factor-alpha is a key inflamm
Staging System and chromosomal abnormalities determined by standard metaphase karyotype and/or fluorescence in situ hybridization (FISH). Treatment-induced adverse events were graded according to the National Cancer Institute common terminology criteria for adverse events (CTCAE) version 4.0. For r
CHOP, COP plui doxorubicin. ,'According to NCI criteria (Cheson el al. 151). (PD) was registered in one patient. Median time to disease progression for patients in PR or SD was 9 months (range, 1-14 months) (Table I). The results of the prehent study, although based on a small number of patients,