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Mesenchymal stem cells that produce neurotrophic factors reduce ischemic damage in the rat middle cerebral artery occlusion model

✍ Scribed by KUROZUMI, K; NAKAMURA, K; TAMIYA, T; KAWANO, Y; ISHII, K; KOBUNE, M; HIRAI, S; UCHIDA, H; SASAKI, K; ITO, Y

Book ID: 126836896
Publisher: Nature Publishing Group
Year: 2005
Tongue: English
Weight: 526 KB
Volume: 11
Category: Article
ISSN: 1525-0016
DOI: 10.1016/j.ymthe.2004.09.020

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## Abstract Intravenous administration of human mesenchymal stem cells (hMSCs) prepared from adult bone marrow has been reported to ameliorate functional deficits after cerebral artery occlusion in rats. Several hypotheses to account for these therapeutic effects have been suggested, and current th