Mercapto steroids in protection against mercury and lead poisoning
β Scribed by Robert T. Blickenstaff; Brian Cox; Emerson Foster; Leslie Roberts; Larry K. Steinrauf
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 416 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0022-3549
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Intraperitoneal doses of 4-dimethylaminophenol hydrochloride (DMAP), hydroxylamine hydrochloride (H2NOH) and sodium nitrite (NaNO2) were found where each converted a maximum of about 37% of the total circulating hemoglobin in mice to methemoglobin. Those doses in mmol/kg were: 0.29 for DMAP, 1.1 for
Mercury is a heavy metal that can cause a variety of toxic effects on the organism, such as hematological and immunological alterations. In the present investigation, deleterious effects of mercury-intoxication in mice and a possible protective effect of diphenyl diselenide (PhSe)(2) were studied. M