Menverins A–D, New Highly Oxygenated Guaiane Lactones from Hainan Gorgonian Menella verrucosa (Brundin)

✍ Scribed by Wen Zhang; Yue-Wei Guo; Ernesto Mollo; Guido Cimino

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: German
• Weight: 107 KB
• Volume: 87
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.200490263

✦ Synopsis

Abstract

Four new highly oxygenated guaiane lactones, menverins A–D (1–4), were isolated from the gorgonian Menella verrucosa (Brundin) from the South China Sea. Their structures and relative configurations were elucidated on the basis of spectroscopic data. All compounds contain a conjugated α‐methyl‐substituted α, β‐unsaturated γ‐lactone moiety, a C(8)C(9) conjugated with the γ‐lactone moiety, and an exocyclic methylene group at C(4) (trivial numbering).