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Menin interacting proteins as clues toward the understanding of multiple endocrine neoplasia type 1

✍ Scribed by Ariane Poisson; Barbara Zablewska; Patrick Gaudray


Book ID
117467556
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
222 KB
Volume
189
Category
Article
ISSN
0304-3835

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We have investigated the endogenous expression of menin, a protein encoded by the gene mutated in multiple endocrine neoplasia type 1 (MEN1). Western blot analysis showed strong expression of menin as a 68 kDa protein in all of 7 human and primate cell lines tested. In a panel of 12 fetal human tiss