IL-18, but not IL-12, is required for op
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Alice E. Denton; Peter C. Doherty; Stephen J. Turner; Nicole L. La Gruta
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Article
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2007
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John Wiley and Sons
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English
⚖ 255 KB
## Abstract The potent innate cytokines IL‐12 and IL‐18 are considered to be important antigen‐independent mediators of IFN‐γ production by NK cells and T lymphocytes. The present analysis addresses the physiological role of IL‐12 and IL‐18 in the generation of virus‐specific CD8^+^ T cells. Both w