Membranous glomerulonephritis in chronic lymphocytic leukemia

✍ Scribed by Panayiotis D. Ziakas; Stavroula Giannouli; Erasmia Psimenou; Lydia Nakopoulou; Michalis Voulgarelis

• Publisher: John Wiley and Sons
• Year: 2004
• Tongue: English
• Weight: 169 KB
• Volume: 76
• Category: Article
• ISSN: 0361-8609
• DOI: 10.1002/ajh.20109

✦ Synopsis

Abstract

We present a case of chronic lymphocytic leukemia associated with nephrotic syndrome. Renal biopsy revealed membranous glomerulonephritis accompanied by interstitial monoclonal lymphocytic infiltration. Combination therapy with cyclophosphamide, vincristine, and prednisone (COP) was successful in inducing an effective response in chronic lymphocytic leukemia. Improvement of renal function and proteinuria was also observed. Am. J. Hematol. 76:271–274, 2004. © 2004 Wiley‐Liss, Inc.