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Membrane viscosity is a major modulating factor of the enterocin CRL35 activity

✍ Scribed by Carlos J. Minahk; Lucila Saavedra; Fernando Sesma; Roberto Morero


Book ID
116308391
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
194 KB
Volume
87
Category
Article
ISSN
0300-9084

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## Abstract The expression of transmembrane transporter multidrug resistance-associated protein 1 (MRP1) confers the multidrug-resistant phenotype (MDR) on cancer cells. Since the activity of the other MDR transporter, P-glycoprotein, is sensitive to membrane perturbation, we aimed to check whether