Membrane-Type Matrix Metalloproteinase 1 Regulates Trophoblast Functions and Is Reduced in Fetal Growth Restriction
✍ Scribed by Hiden, Ursula; Ghaffari-Tabrizi, Nassim; Gauster, Martin; Tam-Amersdorfer, Carmen; Cetin, Irene; Dieber-Rotheneder, Martina; Lang, Uwe; Desoye, Gernot
- Book ID
- 125429773
- Publisher
- American Society for Investigative Pathology
- Year
- 2013
- Tongue
- English
- Weight
- 886 KB
- Volume
- 182
- Category
- Article
- ISSN
- 0002-9440
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Membrane‐type metalloproteinase‐1 (MT1‐MMP) is a transmembrane metalloproteinase overexpressed in tumors, which plays a major role in the first step of pro‐MMP‐2 activation, leading to the generation of an intermediate 62 kDa species. The second step of MMP‐2 activation that yields to t
Hepatocyte growth factor/scatter factor (HGF/SF) contributes to the malignant progression of human gliomas. We investigated the effect of HGF/SF on matrix metalloproteinase-2 (MMP-2), membrane type 1 matrix metalloproteinase (MT1-MMP) and tissue inhibitors of metalloproteinases (TIMPs), expressions