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Membrane type-1 matrix metalloproteinase (MT1-MMP) processing of pro-αv integrin regulates cross-talk between αvβ3 and α2β1 integrinsin breast carcinoma cells

✍ Scribed by Peter C Baciu; E.Aisha Suleiman; Elena I Deryugina; Alex Y Strongin


Book ID
117100002
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
379 KB
Volume
291
Category
Article
ISSN
0014-4827

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Functional activation of integrin αvβ3 i
✍ Elena I. Deryugina; Mario A. Bourdon; Karli Jungwirth; Jeffrey W. Smith; Alex Y. 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 176 KB 👁 1 views

Matrix metalloproteinases (MMPs) and integrins have been implicated in a variety of processes involved in tumor progression. To evaluate the individual roles of integrin alphavbeta3 and membrane-type 1 matrix metalloproteinase (MT1-MMP), as well as the effects of their joint expression on tumor cell