Membrane Proteins as Drug Targets

✍ Scribed by Charles A. Lunn (Eds.)

Publisher: Academic Press, Elsevier
Year: 2010
Leaves: 247
Series: Progress in Molecular Biology and Translational Science 91
Category: Library

No coin nor oath required. For personal study only.

✦ Table of Contents

Content:
Copyright Page
Page iv

Contributors
Pages ix-x

Preface
Page xi
Charles A. Lunn

Chapter 1 - Inverse Agonism at Serotonin and Cannabinoid Receptors
Pages 1-40
Vincent J. Aloyo, Kelly A. Berg, William P. Clarke, Umberto Spampinato, John A. Harvey

Chapter 2 - G Protein-Coupled Receptor Heteromers as New Targets for Drug Development
Pages 41-52
Sergi Ferré, Gemma Navarro, Vicent Casadó, Antoni Cortés, Josefa Mallol, Enric I. Canela, Carme Lluís, Rafael Franco

Chapter 3 - Receptor Activity Modifying Proteins and Their Potential as Drug Targets
Pages 53-79
Denise L. Wootten, John Simms, Debbie L. Hay, Arthur Christopoulos, Patrick M. Sexton

Chapter 4 - Regulators of G Protein Signaling Proteins as Targets for Drug Discovery
Pages 81-119
Benita Sjögren, Levi L. Blazer, Richard R. Neubig

Chapter 5 - Escorts Take the Lead: Molecular Chaperones as Therapeutic Targets
Pages 121-149
Dumaine Williams, Lakshmi A. Devi

Chapter 6 - The T1R2/T1R3 Sweet Receptor and TRPM5 Ion Channel: Taste Targets with Therapeutic Potential
Pages 151-208
Dennis Sprous, R. Kyle Palmer

Chapter 7 - Challenges and Approaches for Assay Development of Membrane and Membrane-Associated Proteins in Drug Discovery
Pages 209-239
Scott Gridley, Anthony L. Shrout, Edward A. Esposito

Subject Index
Pages 241-247

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