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Membrane potential modulation of ionomycin-stimulated Ca2+entry via Ca2+/H+exchange and SOC in rat submandibular acinar cells

✍ Scribed by Hideyo Yoshida; Chikara Hirono; Chikao Shimamoto; Eriko Daikoku; Takahiro Kubota; Makoto Sugita; Yoshiki Shiba; Takashi Nakahari

Book ID: 107667875
Publisher: Springer Japan
Year: 2010
Tongue: English
Weight: 358 KB
Volume: 60
Category: Article
ISSN: 1880-6546
DOI: 10.1007/s12576-010-0098-7

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The effects of protein kinase C (PKC) activation and inhibition on the inositol 1,4,5-trisphosphate (IP 3 ) and cytosolic Ca 2ϩ ([Ca 2ϩ ] i ) responses of rat submandibular acinar cells were investigated. IP 3 formation in response to acetylcholine (ACh) was not affected by the PKC activator phorbol