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Membrane mechanisms of the effects of apamin on ion currents in smooth muscle cells

✍ Scribed by O. V. Povstyan; V. V. Rekalov; M. F. Shuba

Publisher
Springer US
Year
2000
Tongue
English
Weight
215 KB
Volume
32
Category
Article
ISSN
0090-2977

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✍ A. V. Zholos; L. V. Baidan; M. F. Shuba πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 820 KB

The patch-clamp method has been used to investigate the action of caffeine on the calcium current (Ic,) in single isolated smooth muscle cells of the guineapig ileum. Caffeine (10 mM) substantially inhibited Ic,. This effect occurred in a biphasic manner and it was not due either to activation of ad