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Membrane Localization of the Electrogenic Cation Transporter rOCT1 in Rat Liver

โœ Scribed by Friederike Meyer-Wentrup; Ullrich Karbach; Valentin Gorboulev; Petra Arndt; Hermann Koepsell

Book ID
115582443
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
1005 KB
Volume
248
Category
Article
ISSN
0006-291X

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Down-regulation of the organic cation tr
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โœ Gerald U. Denk; Carol J. Soroka; Albert Mennone; Hermann Koepsell; Ulrich Beuers ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 200 KB

The liver plays a major role in biotransformation and elimination of various therapeutic agents and xenobiotics, many of which are organic cations and substrates of the organic cation transporter 1 (Oct1, Slc22a1). Oct1 is expressed at the basolateral membranes of hepatocytes and proximal renal tubu