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Membrane interaction and secondary structure of de novo designed arginine-and tryptophan peptides with dual function

✍ Scribed by Hanna A. Rydberg; Nils Carlsson; Bengt Nordén


Book ID
119194581
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
416 KB
Volume
427
Category
Article
ISSN
0006-291X

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## Abstract We introduce a de novo designed peptide model system that enables the systematic study of 1) the role of a membrane environment in coiled‐coil peptide folding, 2) the impact of different domains of an α‐helical coiled‐coil heptad repeat on the interaction with membranes, and 3) the dyna