Membrane Fluidity

✍ Scribed by Joan M. Boggs (auth.), Morris Kates, Lionel A. Manson (eds.)

• Publisher: Springer US
• Year: 1984
• Tongue: English
• Leaves: 697
• Series: Biomembranes 12
• Edition: 1
• Category: Library

✦ Synopsis

The aim of this book is to bring together in one volume the current research and thought on the concept of membrane fluidity as a biological phenomenon. The invited articles are intended to review recent develop­ ments in the areas of membrane research covered and to summarize the current concepts and theories in those areas. The authors have been given ample opportunity to present their thoughts and speculation on membrane fluidity and related phenomena in a more expanded form than is usually possible in reviews of this type. It is hoped that this approach will have a stimulating effect on research and theoretical development in the biomem­ brane field. The chapters in this book are arranged in three sections, the first of which covers physical studies of membrane fluidity and related phenomena on the molecular level. Included are chapters on intermolecular hydrogen bonding between membrane lipids, thermal analysis of membranes, appli­ cation of fluorescence and NMR spectrometry to the study of membrane fluidity, and the effect of drugs and other compounds on membrane stability and fluidity. The second section deals with the regulation of membrane fluidity in microorganisms, plants, and higher organisms by factors such as tem­ perature, fatty acid chain length, lipid desaturation, and polar head group structure.

✦ Table of Contents

Front Matter....Pages i-xxi
Front Matter....Pages 1-1
Intermolecular Hydrogen Bonding between Membrane Lipids....Pages 3-53
Thermal Analysis of Membranes....Pages 55-97
Fluorescence Polarization Studies of Membrane Fluidity: Where Do We Go from Here?....Pages 99-131
Conformational and Motional Properties of Lipids in Biological Membranes as Determined by Deuterium Magnetic Resonance....Pages 133-168
Fluidity of Cell Membranes in the Presence of Some Drugs and Inhibitors....Pages 169-203
Lipid Bilayer Stability in Biological Membranes....Pages 205-245
Front Matter....Pages 247-247
The Relationship between Membrane Lipid Fluidity and Phase State and the Ability of Bacteria and Mycoplasmas to Grow and Survive at Various Temperatures....Pages 249-278
Thermal Control of Fatty Acid Synthetases in Bacteria....Pages 279-301
Regulation and Pathways of Membrane Lipid Biosynthesis in Bacilli....Pages 303-327
The Regulation of Membrane Fluidity in Bacteria by Acyl Chain Length Changes....Pages 329-347
The Control of Membrane Fluidity in Plasmalogen-Containing Anaerobic Bacteria....Pages 349-377
Regulation of Membrane Fluidity by Lipid Desaturases....Pages 379-395
The Regulation of Membrane Fluidity in Tetrahymena ....Pages 397-432
Control of Membrane Fluidity in Fusarium ....Pages 433-450
Regulation of Hepatic Phospholipid N -Methylation....Pages 451-471
Front Matter....Pages 473-473
Fluidity of Membrane Lipids....Pages 475-516
Membrane Lipid Adaptation in Yeast....Pages 517-542
The Dynamic State of Membrane Lipids: The Significance of Lipid Exchange and Transfer Reactions to Biomembrane Composition, Structure, Function, and Cellular Lipid Metabolism....Pages 543-562
Role of Phospholipid Head Group Structure and Polarity in the Control of Membrane Fusion....Pages 563-583
Membrane Fluidity and Receptor Function....Pages 585-601
Front Matter....Pages 473-473
Glycosphingolipid Domain Formation and Lymphocyte Activation....Pages 603-632
Dynamics of Membrane Lipids during Lymphocyte Stimulation by Mitogens....Pages 633-660
Membrane Permeability in Porcine Malignant Hyperthermia....Pages 661-687
Back Matter....Pages 689-693

✦ Subjects

Biochemistry, general