Stretch-induced membrane type matrix met
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Suresh C. Tyagi; Kendall Lewis; Darius Pikes; Alton Marcello; Vibhas S. Mujumdar
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Article
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1998
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John Wiley and Sons
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English
โ 274 KB
๐ 1 views
In the normal heart, cardiomyocytes are surrounded by extracellular matrix (ECM) and latent matrix metalloproteinases (MMPs), which are produced primarily by cardiac fibroblasts. An activator of latent MMPs might be induced by ischemic conditions or pressure-induced stretching. To test the hypothesi