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Membrane depolarization by activation of prostaglandin E receptor EP3subtype of putative serotonergic neurons in the dorsal raphe nucleus of the rat

✍ Scribed by Toshihiko Momiyama; Naoyuki Todo; Yukihiko Sugimoto; Atsushi Ichikawa; Shuh Narumiya


Publisher
Springer-Verlag
Year
1996
Tongue
English
Weight
561 KB
Volume
353
Category
Article
ISSN
0028-1298

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The activation of neurosecretory neurons that express corticotropin-releasing hormone (CRH) in response to increased circulating levels of interleukin-1␀ (IL-1␀) depends on prostaglandin E 2 (PGE 2 ) acting locally within the brain parenchyma. To identify potential central targets for PGE 2 relevant