Homocysteic acid induces intraneuronal a
✍
Tohru Hasegawa; Wataru Ukai; Dong-Gyu Jo; Xiangru Xu; Mark P. Mattson; Masaya Na
📂
Article
📅
2005
🏛
John Wiley and Sons
🌐
English
⚖ 228 KB
The causes of neuronal dysfunction and degeneration in Alzheimer's disease (AD) are not fully understood, but increased production of neurotoxic forms of amyloid b-peptide-42 (Ab42) seems of major importance. Large extracellular deposits of aggregated Ab42 (plaques) is a diagnostic feature of AD, bu