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Membrane-bound protein kinase activity in acetylcholine receptor-enriched membranes

✍ Scribed by Adrienne S. Gordon; C. Geoffrey Davis; Dale Milfay; Jasminder Kaur; Ivan Diamond

Book ID
115724793
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
652 KB
Volume
600
Category
Article
ISSN
0005-2736

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When the acetylcholine receptor (AChR) from Torpedo is phosphorylated, ATP is found to bind non-covalently to the preparation. After correction is made for this binding of ATP, the phosphorylation reaction has a Km of 0,16 mM, a pH optimum of 8,6 and reaches maximal activity within 3 min. The intrin