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Membrane attack complex of complement and 20 kDa homologous restriction factor (CD59) in myocardial infarction

โœ Scribed by Toyohiro Tada; Hidechika Okada; Noriko Okada; Hisashi Tateyama; Harumi Suzuki; Youhei Takahashi; Tadaaki Eimoto


Book ID
105067990
Publisher
Springer
Year
1997
Tongue
English
Weight
858 KB
Volume
430
Category
Article
ISSN
1432-2307

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Human CD59 is a small membrane-bound glycoprotein that functions as an inhibitor of the membrane-attack complex (MAC) of the complement system by binding the complement proteins C8 and C9. The crystal structure of a soluble construct of CD59 has been determined to 2.1 A resolution. When compared wit