✦ LIBER ✦

Membrane-associated ribosomes in producing and nonproducing mouse myeloma cells

✍ Scribed by William Cieplinski; M. D. Scharff

Book ID: 102884527
Publisher: John Wiley and Sons
Year: 1980
Tongue: English
Weight: 775 KB
Volume: 103
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1041030310

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✦ Synopsis

Abstract

Mouse myeloma cell lines synthesize large amounts of immunoglobulin on their membrane‐associated polyribosomes. Variants which no longer synthesize immunoglobulins have been studied and shown to have the same number of tightly bound membrane‐associated polyribosomes as the parental cell lines. These polyribosomes are still active in the synthesis of nonimmunoglobulin proteins.

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