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Membrane assembly of the cholesterol-dependent cytolysin pore complex

โœ Scribed by Eileen M. Hotze; Rodney K. Tweten

Book ID
116275204
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
781 KB
Volume
1818
Category
Article
ISSN
0005-2736

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โœ Anderluh, Gregor; Lakey, Jeremy ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› Springer New York ๐ŸŒ English โš– 287 KB

Formation of transmembrane pores is a very effective way of killing cells. It is thus not surprising that many bacterial and eukaryotic toxic agents are pore-forming proteins. Pore formation in a target membrane is a complex process composed of several steps; proteins need to attach to the lipid mem