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Membrane adsorbers extend parvovirus filter life


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
68 KB
Volume
106
Category
Article
ISSN
0006-3592

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## Abstract Pre‐filtration using ion exchange membrane adsorbers can improve parvovirus filter throughput of monoclonal antibodies (mAbs). The membranes work by binding trace foulants, and although some antibody product also binds, yields β‰₯99% are easily achieved by overloading. Results show that f