NMDA antagonists potentiate antiparkinso
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Dr Thomas Klockgether; Lechoslaw Turski
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Article
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1990
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John Wiley and Sons
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English
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Systemically administered N-methybaspartate (NMDA) antagonists, MK-80 1 (( + )5-methyl-l0,1 l-dihydro-5Hdibenzo(a,d)cyclohepten-5,IO-imine maleate) and CPP (34( i-)-2-carboxypiperazin-4-yl}-propyl-I-phosphonate), potentiate the ability of L-dopa (~-3,4-dihydroxyphenylalanine) to reverse akinesia and