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Melatonin Synthesis in the Hen Pineal Gland and its Control by Light

โœ Scribed by AXELROD, JULIUS; WURTMAN, RICHARD J.; WINGET, CHARLES M.

Book ID
109632363
Publisher
Nature Publishing Group
Year
1964
Tongue
English
Weight
133 KB
Volume
201
Category
Article
ISSN
0028-0836

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The nocturnal pattern of Syrian hamster pineal melatonin synthesis is characterized by a 6-8 h lag period, followed by a late-night, short-duration peak in both N-acetyltransferase (NAT) activity and melatonin content. Administration of cycloheximide (20 mgkg body weight) given either at the time of