Melatonin reduces oxidative stress induced by ochratoxin A in rat liver and kidney
✍ Scribed by Abdel-Raheim M.A. Meki; Ahmed A.A. Hussein
- Book ID
- 117794240
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- English
- Weight
- 124 KB
- Volume
- 130
- Category
- Article
- ISSN
- 1532-0456
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## Abstract Cholestasis, encountered in a variety of clinical disorders, is characterized by intracellular accumulation of toxic bile acids in the liver. Furthermore, oxidative stress plays an important role in the pathogenesis of bile acids. Taurolithocholic acid (TLC) was revealed in previous stu
## Abstract Epidemiological studies indicate that ochratoxin A (OTA) may be involved in the pathogenesis of different forms of human nephropathies. Melatonin (MEL) displays antioxidant and free radical scavenger properties. In the present study, the effect of MEL on the oxidative stress induced by