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Melatonin reduces membrane rigidity and oxidative damage in the brain of SAMP8 mice

✍ Scribed by J.J. García; G. Piñol-Ripoll; E. Martínez-Ballarín; L. Fuentes-Broto; F.J. Miana-Mena; C. Venegas; B. Caballero; G. Escames; A. Coto-Montes; D. Acuña-Castroviejo

Book ID
116781577
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
850 KB
Volume
32
Category
Article
ISSN
0197-4580

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## Abstract Numerous data indicate that hyperhomocysteinemia is a risk factor for cardio‐ and cerebrovascular diseases. At least in part, homocysteine (HCY) impairs cerebrovascular function because it generates large numbers of free radicals. Since melatonin is a well‐known antioxidant, which reduc