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Melatonin Protects Against Oxidative Organ Injury in a Rat Model of Sepsis

✍ Scribed by Göksel Şener; Hale Toklu; Caner Kapucu; Feriha Ercan; Gözde Erkanlı; Ayhan Kaçmaz; Metin Tilki; Berrak Ç. Yeğen

Book ID: 113048146
Publisher: Springer
Year: 2004
Tongue: English
Weight: 294 KB
Volume: 35
Category: Article
ISSN: 1436-2813
DOI: 10.1007/s00595-004-2879-1

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## Abstract Cholestasis, encountered in a variety of clinical disorders, is characterized by intracellular accumulation of toxic bile acids in the liver. Furthermore, oxidative stress plays an important role in the pathogenesis of bile acids. Taurolithocholic acid (TLC) was revealed in previous stu