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Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells

✍ Scribed by Abdulhadi C. Uguz; Bilal Cig; Javier Espino; Ignacio Bejarano; Mustafa Naziroglu; Ana B. Rodríguez; José A. Pariente

Book ID
111264946
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
546 KB
Volume
53
Category
Article
ISSN
0742-3098

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## Abstract Melatonin is a natural compound synthesized by a variety of organs. It has been described to possess cell protecting activity in normal cells but was shown to induce apoptotic cell death in cancer cells. We determined to which extent and based on which molecular mechanisms melatonin is