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Melatonin Inhibits Proliferation and Melanogenesis in Rodent Melanoma Cells

✍ Scribed by Andrzej Slominski; Daniel Pruski


Book ID
115601474
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
332 KB
Volume
206
Category
Article
ISSN
0014-4827

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## Abstract Activating __BRAF__ mutations and loss of wild‐type __INK4A__ expression both occur at high frequencies in melanomas. Here, we present evidence that __BRAF__ and __INK4A__ have different effects on melanogenesis, a marker of melanocytic differentiation. Human melanoma cell line 624Mel h