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Melatonin increases survival of HaCaT keratinocytes by suppressing UV-induced apoptosis

✍ Scribed by T. W. Fischer; B. Zbytek; R. M. Sayre; E. O. Apostolov; A. G. Basnakian; T. W. Sweatman; J. Wortsman; P. Elsner; A. Slominski

Book ID: 111264279
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 448 KB
Volume: 40
Category: Article
ISSN: 0742-3098
DOI: 10.1111/j.1600-079x.2005.00273.x

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## Abstract Melatonin is a natural compound synthesized by a variety of organs. It has been described to possess cell protecting activity in normal cells but was shown to induce apoptotic cell death in cancer cells. We determined to which extent and based on which molecular mechanisms melatonin is