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Melatonin Decreases Nitric oxide Production, Inducible Nitric oxide Synthase Expression and Lipid Peroxidation Induced by Venezuelan Encephalitis Equine Virus in Neuroblastoma Cell Cultures

โœ Scribed by Nereida Valero; Luz Marina Espina; Jesus Mosquera


Publisher
Springer
Year
2006
Tongue
English
Weight
208 KB
Volume
31
Category
Article
ISSN
0364-3190

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Excessive nitric oxide (NO) generated by hepatic cells in response to lipopolysaccharide (LPS) and inflammatory substances (e.g., platelet-activating factor [PAF]) is a key contributor to the pathophysiological outcomes observed in the liver during sepsis. In rats subjected to liver-focused endotoxe