## Background: The Harderian gland (HG) is a tubulo-alveolar gland found within the ocular orbit of animals which present a nictitating membrane. The Harderian gland is regarded as an extrapineal melatonin producing organ and both, photoperiod and melatonin have been shown to exert an important ro
Melatonin and porphyrin in the harderian glands of the syrian hamster: Orcadian patterns and response to autumnal conditions
✍ Scribed by Gerald R. Buzzell; Andreas Pangerl; Brigitte Pangerl; Armando Menendez-Pelaez; Mary K. Vaughan; John C. Little; Steven M. Hill; George M. Vaughan; Russel J. Reiter
- Publisher
- Elsevier Science
- Year
- 1990
- Tongue
- English
- Weight
- 672 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0020-711X
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The Harderian glands in Syrian hamsters exhibit a striking sexual dimorphism. Male Harderian glands show two cell types and low levels of porphyrins and melatonin. Of the enzymes involved in the synthesis of melatonin, N-acetyltransferase (NAT) and hydroxyindole-0methyltransferase (HIOMT) show high
Sexual differences on thyroxine 5'-deiodinase (5'-D) in the Harderian gland of Syrian hamsters were investigated. We compared the 24-h profile of 5'-D activity in male and female hamsters, observing a clear rhythm in males but not in females. Female values were always significantly higher than male
N-acetyltransferase (NAT) activity in the Harderian glands of intact and gonadectomized male and female Syrian hamsters was evaluated. The exogenous administration of Sa-dihydrotestosterone (DHT) to castrated males and intact females produced an increase in NAT values, which reached the values prese